Opportunity Information: Apply for 7200AA25RFA00003

The Harmonization of systems and services to embed HIV service delivery into primary health care (HARMONIZE) opportunity is a USAID funding call for a large-scale health program to better integrate HIV services into routine primary health care systems. USAID is looking for a qualified implementer to run HARMONIZE through a cooperative agreement, which typically means USAID expects substantial involvement during implementation (for example, collaborating on technical direction, monitoring, and key decisions) rather than simply issuing a grant with minimal engagement. The core idea reflected in the title and description is harmonization: aligning and strengthening the underlying systems and service delivery approaches so HIV prevention, testing, treatment, and related care are embedded within primary care settings, instead of operating as isolated or parallel HIV-only services.

This is a discretionary funding opportunity administered by the U.S. Agency for International Development under the health funding activity category (CFDA/Assistance Listing 98.001). The funding opportunity number is 7200AA25RFA00003, and it was created on January 16, 2025. Applications were originally due on February 28, 2025, and the posting notes the opportunity may be amended, meaning applicants are expected to monitor Grants.gov for updates, changes, or clarifications that could affect eligibility, requirements, or deadlines.

In terms of who can apply, the listing indicates eligible applicants include nonprofits with 501(c)(3) status (other than institutions of higher education). At the same time, the narrative text states eligibility is not restricted, which can happen when a synopsis is broad but the formal eligibility rules are defined in the Notice of Funding Opportunity (NOFO) itself. In practical terms, anyone considering applying should treat the NOFO as the controlling document and confirm the exact eligibility standards in Section B, because that section is what USAID will use to determine whether an application can be considered for award.

Financially, this is an unusually large award: the ceiling is $780,000,000, and USAID anticipates making one award. That combination suggests USAID is seeking a single prime implementer to lead a major, multi-faceted program, potentially with multiple partners or subrecipients, and to deliver results at scale. USAID also makes clear that award decisions will be based on the merit review criteria in the NOFO and will be subject to a risk assessment, meaning the technical strength of the proposal matters, but so do factors like organizational capacity, past performance, internal controls, financial management, and compliance readiness.

Operationally, the posting emphasizes that applicants need to read the NOFO closely to understand what USAID is asking for, how to submit, and how selections will be made. To be eligible for an award, applicants must provide all required information and meet the stated standards, which typically include completing mandatory forms, meeting formatting and submission rules, and addressing all required technical and management sections. The notice also places responsibility on applicants to download the full opportunity package from Grants.gov and to ensure they are working from the complete and most current version; USAID disclaims responsibility for errors caused by data transmission or file conversion, which is a reminder to validate that the downloaded materials are intact and complete before building a submission around them.

Finally, the opportunity directs applicants needing technical help with Grants.gov registration or access issues to contact the Grants.gov Support Center at 1-800-518-4726 or support@grants.gov. That detail matters because registration, account roles, and submission permissions can take time to set up, and technical issues close to the deadline can jeopardize submission. The main takeaway is that HARMONIZE is a single-award, high-value cooperative agreement focused on integrating HIV service delivery into primary health care through harmonized systems and services, with selection determined by a formal merit review and risk assessment process laid out in the NOFO on Grants.gov.

  • The Agency for International Development in the health sector is offering a public funding opportunity titled "Harmonization of systems and services to embed HIV service delivery into primary health care (HARMONIZE)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 98.001.
  • This funding opportunity was created on 2025-01-16.
  • Applicants must submit their applications by 2025-02-28. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $780,000,000.00 in funding.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education.
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HARMONIZE (USAID) Grant Opportunity FAQs

What is the HARMONIZE opportunity?

HARMONIZE stands for Harmonization of systems and services to embed HIV service delivery into primary health care. It is a USAID funding opportunity for a large-scale health program focused on integrating HIV prevention, testing, treatment, and related care into routine primary health care systems rather than operating separate, parallel HIV-only services.

What agency is offering this funding opportunity?

The opportunity is administered by the U.S. Agency for International Development (USAID).

What type of funding instrument is USAID planning to use?

USAID intends to make an award through a cooperative agreement. A cooperative agreement typically involves substantial USAID involvement during implementation, such as collaboration on technical direction, monitoring, and key decisions, rather than minimal engagement after award.

What is the main program goal described in the posting?

The central goal is harmonization: aligning and strengthening systems and service delivery approaches so HIV services are embedded into primary health care settings, improving integration and reducing reliance on stand-alone HIV service platforms.

Is this a discretionary funding opportunity?

Yes. The posting describes HARMONIZE as a discretionary funding opportunity.

What is the Assistance Listing (CFDA) number for this opportunity?

The Assistance Listing (formerly CFDA) is 98.001, under the health funding activity category.

What is the funding opportunity number?

The funding opportunity number is 7200AA25RFA00003.

When was the opportunity created?

The listing indicates it was created on January 16, 2025.

What was the original application deadline?

Applications were originally due on February 28, 2025.

Can the opportunity be amended after posting?

Yes. The posting notes the opportunity may be amended. Applicants are expected to monitor Grants.gov for updates, changes, or clarifications that could affect eligibility, requirements, or deadlines.

Who is eligible to apply?

The listing indicates eligible applicants include nonprofits with 501(c)(3) status (other than institutions of higher education). However, the narrative also states eligibility is not restricted. Because these statements can differ between a synopsis and the full solicitation, applicants should treat the Notice of Funding Opportunity (NOFO) as controlling and confirm eligibility requirements in the NOFO (especially Section B).

If the synopsis says one thing and the NOFO says another, which rules apply?

The NOFO is the controlling document. USAID will use the eligibility and application requirements as written in the NOFO (including Section B for eligibility) when determining whether an application can be considered for award.

How much funding is available?

The award ceiling is $780,000,000.

How many awards does USAID expect to make?

USAID anticipates making one award.

What does a single award with a very large ceiling suggest about the program structure?

It suggests USAID is likely seeking a single prime implementer to lead a major, multi-faceted program at scale, potentially coordinating multiple partners or subrecipients.

How will USAID decide who receives the award?

Award decisions will be based on the merit review criteria in the NOFO and will also be subject to a risk assessment.

What does “risk assessment” mean in this context?

In addition to proposal quality, USAID will consider factors such as organizational capacity, past performance, internal controls, financial management, and compliance readiness when assessing risk.

What should applicants do to understand what USAID is asking for?

Applicants should read the NOFO closely to understand the program expectations, required application components, submission instructions, and how selections will be made.

What are common requirements to remain eligible for award consideration?

The posting emphasizes that applicants must provide all required information and meet stated standards. This typically includes completing mandatory forms and meeting formatting and submission rules, and fully addressing required technical and management sections as specified in the NOFO.

Where do applicants access the full opportunity package?

Applicants are responsible for downloading the full opportunity package from Grants.gov and ensuring they are working from the complete and most current version.

Why is it important to verify the downloaded application package?

USAID disclaims responsibility for errors caused by data transmission or file conversion. Applicants should confirm the downloaded materials are intact and complete before developing and submitting an application.

Where should applicants look for official updates or clarifications?

Applicants should monitor the opportunity on Grants.gov for amendments, updates, and clarifications.

Who should applicants contact for Grants.gov technical help?

For Grants.gov registration or access issues, applicants should contact the Grants.gov Support Center at 1-800-518-4726 or support@grants.gov.

Why does Grants.gov registration and access matter for this opportunity?

The posting highlights that registration, account roles, and submission permissions can take time to set up. Technical issues close to the deadline can jeopardize submission, so applicants should address access and registration early.

What is the overall takeaway from the posting?

HARMONIZE is a single-award, high-value USAID cooperative agreement focused on integrating HIV service delivery into primary health care through harmonized systems and services. Selection will follow the formal merit review and risk assessment process described in the NOFO on Grants.gov.

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